Arachidonoyl amide

Arachidonoyl amide
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay10007295-5 5 mg -

6 - 10 Werktage*

42,00 €
Cay10007295-10 10 mg -

6 - 10 Werktage*

79,00 €
Cay10007295-25 25 mg -

6 - 10 Werktage*

187,00 €
Cay10007295-50 50 mg -

6 - 10 Werktage*

330,00 €
 
Anandamide (AEA) is an endogenous cannabinoid that binds to both central cannabinoid (CB1) and... mehr
Produktinformationen "Arachidonoyl amide"
Anandamide (AEA) is an endogenous cannabinoid that binds to both central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. The biological actions of AEA are terminated by cellular uptake and hydrolysis of the amide bond by the enzyme fatty acid amide hydrolase (FAAH). Arachidonoyl amide is an analog of anandamide (AEA) that lacks the hydroxyethyl moiety. It is hydrolyzed by FAAH more effectively than AEA but exhibits significantly weaker binding to the human CB1 receptor with a Ki of 9.6 µM. Arachidonoyl amide and AEA exhibit similar binding and translocation into cells via the AEA transporter. It inhibits [3H]-AEA uptake into human astrocytoma cells with an IC50 of 9 µM. Arachidonoyl amide also inhibits rat glial gap junction cell-cell communication by 90% at a concentration of 20 µM. Formal Name: 5Z,8Z,11Z,14Z-eicosatetraenamide. CAS Number: 85146-53-8. Synonyms: Arachidonamide, Arachidonic Acid amide. Molecular Formula: C20H33NO. Formula Weight: 303.5. Purity: >98%. Formulation: A solution in methyl acetate. Solubility: 0.1 M Na2CO3: 1 mg/ml, DMF: 10 mg/ml, DMSO: 10 mg/ml, Ethanol: 10 mg/ml. SMILES: CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)N. InChi Code: InChI=1S/C20H33NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H2,21,22)/b7-6-,10-9-,13-12-,16-15-. InChi Key: BNBSCAZCQDLUDU-DOFZRALJSA-N.
Schlagworte: Arachidonamide, Arachidonic Acid amide, 5Z,8Z,11Z,14Z-eicosatetraenamide
Hersteller: Cayman Chemical
Hersteller-Nr: 10007295

Eigenschaften

Anwendung: Bioactive lipid assays
MW: 303.5 D
Formel: C20H33NO
Reinheit: >98%
Format: Solution

Datenbank Information

CAS : 85146-53-8| Finde Alternativen

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Signalwort: Danger
GHS-Piktogramme:
H-Sätze: EUH066, H225, H319, H336
P-Sätze: , P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P303+361+353, P304+340, P305+351+338, P312, P337+313, P370+378, P403+233, P403+235, P405, P501
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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