alpha-Muricholic Acid

alpha-Muricholic acid is a murine-specific primary bile acid. Dietary administration of soybean protein decreases fecal levels of alpha-muricholic acid in mice with high-fat diet-induced obesity which correlates with increases in fecal Clostridium cluster XIVa, a major producer of secondary bile acids. Plasma, liver, and muscle levels of alpha-muricholic acid are increased in mice switched from a high-fat to low-fat diet.Formal Name: (3alpha,5beta,6beta,7alpha)-3,6,7-trihydroxy-cholan-24-oic acid. CAS Number: 2393-58-0. Synonyms: 5beta-Cholanic Acid-3alpha,6beta,7alpha-triol, alpha-MCA. Molecular Formula: C24H40O5. Formula Weight: 408.6. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml, DMSO: 20 mg/ml, Ethanol: 20 mg/ml. SMILES: C[C@H](CCC(O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])[C@H](O)[C@@H](O)[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C. InChi Code: InChI=1S/C24H40O5/c1-13(4-7-19(26)27)15-5-6-16-20-17(9-11-23(15,16)2)24(3)10-8-14(25)12-18(24)21(28)22(20)29/h13-18,20-22,25,28-29H,4-12H2,1-3H3,(H,26,27)/t13-,14-,15-,16+,17+,18+,20+,21+,22+,23-,24-/m1/s1. InChi Key: DKPMWHFRUGMUKF-GDYCBZMLSA-N.