alpha-hydroxy Farnesyl Phosphonic Acid

alpha-hydroxy Farnesyl phosphonic acid is a nonhydrolyzable analog of farnesyl pyrophosphate which acts as a competitive inhibitor of farnesyl transferase (FTase). At concentrations greater than 1 µM, alpha-hydroxy farnesyl phosphonic acid inhibits the processing of Ras in Ha-ras-transformed NIH3T3 cells.Formal Name: (±)-1-hydroxy-3,7,11-trimethyl-2E,6E,10-dodecatriene-1-phosphonic acid. CAS Number: 148796-53-6. Synonyms: Hydroxyfarnesyl Phosphate. Molecular Formula: C15H27O4P. Formula Weight: 302.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: 10 mM Na2CO3: freely soluble, ETOH: >25 mg/ml, PBS pH 7.2: <25 µg/ml. SMILES: C/C(=C\CC\C(=C\C(O)P(=O)(O)O)\C)/CCC=C(C)C. InChi Code: InChI=1S/C15H27O4P/c1-12(2)7-5-8-13(3)9-6-10-14(4)11-15(16)20(17,18)19/h7,9,11,15-16H,5-6,8,10H2,1-4H3,(H2,17,18,19)/b13-9+,14-11+. InChi Key: MONZTFSZTWQCKH-IJFRVEDASA-N.