Acecainide (hydrochloride)

Acecainide is an active metabolite of the class III antiarrhythmic procainamide. It is formed from procainamide via hepatic N-acetyltransferases. Acecainide prevents hypoxia-induced ventricular fibrillation in mice and decreases arrhythmia induced by aconitine in dogs. Acecainide (10 µM), when used in high-fat medium, decreases lipid droplet area by greater than 50% in SK-Hep1 cells without inducing cytotoxicity but does not affect lipid droplets in primary mouse hepatocytes.Formal Name: 4-(acetylamino)-N-[2-(diethylamino)ethyl]-benzamide, monohydrochloride. CAS Number: 34118-92-8. Synonyms: N-Acetylprocainamide. Molecular Formula: C15H23N3O2 . HCl. Formula Weight: 313.8. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 14 mg/ml, Ethanol: 16 mg/ml, PBS (pH 7.2): 10 mg/ml. lambdamax: 272 nm. SMILES: CC(NC1=CC=C(C(NCCN(CC)CC)=O)C=C1)=O.Cl. InChi Code: InChI=1S/C15H23N3O2.ClH/c1-4-18(5-2)11-10-16-15(20)13-6-8-14(9-7-13)17-12(3)19,/h6-9H,4-5,10-11H2,1-3H3,(H,16,20)(H,17,19),1H. InChi Key: IYEWBJUCJHKLHD-UHFFFAOYSA-N.