9-Nitrooleate

9-Nitrooleate
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay10008042-50 50 µg -

6 - 10 Werktage*

32,00 €
Cay10008042-100 100 µg -

6 - 10 Werktage*

50,00 €
Cay10008042-500 500 µg -

6 - 10 Werktage*

210,00 €
Cay10008042-1 1 mg -

6 - 10 Werktage*

369,00 €
 
Nitrated unsaturated fatty acids, such as 10- and 12-nitrolinoleate (LNO2, Cay-10037),... mehr
Produktinformationen "9-Nitrooleate"
Nitrated unsaturated fatty acids, such as 10- and 12-nitrolinoleate (LNO2, Cay-10037), cholesteryl nitrolinoleate, and nitrohydroxylinoleate, represent a new class of endogenous lipid-derived signalling molecules. LNO2 isomers serve as potent endogenous ligands for PPARgamma and can also decompose or be metabolized to release nitric oxide. 9-Nitrooleate is one of two regioisomers of nitrooleate, the other being 10-nitrooleate (Cay-10008043) (OA-NO2, used for the mixture of isomers), which are formed by nitration of oleic acid in approximately equal proportions in vivo. Peroxynitrite, acidified nitrite, and myeloperoxidase in the presence of H2O2 and nitrite, all mediate the nitration of oleic acid. OA-NO2 is found in human plasma as the free acid and esterified in phospholipids at concentrations of 619 ± 52 nM and 302 ± 369 nM, respectively. OA-NO2 activates PPARgamma approximately 7-fold at a concentration of 1 µM and effectively promotes the differentiation of 3T3-L1 preadiopcytes to adipocytes at 3 µM. Formal Name: 9-nitro-9E-octadecenoic acid. CAS Number: 875685-44-2. Synonyms: 9-Nitrooleic Acid, 9-nitro-9-trans-Octadecenoic Acid. Molecular Formula: C18H33NO4. Formula Weight: 327.5. Purity: >98%. Formulation: A solution in ethanol. Solubility: Ethanol: 1 mg/ml. lambdamax: 255 nm. SMILES: CCCCCCCC/C=C([N+]([O-])=O)\CCCCCCCC(O)=O. InChi Code: InChI=1S/C18H33NO4/c1-2-3-4-5-6-8-11-14-17(19(22)23)15-12-9-7-10-13-16-18(20)21/h14H,2-13,15-16H2,1H3,(H,20,21)/b17-14+. InChi Key: CQOAKBVRRVHWKV-SAPNQHFASA-N.
Schlagworte: 9-nitro-9-trans-Octadecenoic Acid, 9-Nitrooleic Acid, 9-nitro-9E-octadecenoic acid
Hersteller: Cayman Chemical
Hersteller-Nr: 10008042

Eigenschaften

Anwendung: Bioactive lipid assays
MW: 327.5 D
Formel: C18H33NO4
Reinheit: >98%
Format: Solution

Datenbank Information

CAS : 875685-44-2| Finde Alternativen

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Signalwort: Danger
GHS-Piktogramme:
H-Sätze: H225
P-Sätze: P210, P233, P240, P241, P242, P243, P280, P303+361+353, P370+378, P403+235, P501
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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