8,12-iso-iPF2alpha-VI

8,12-iso-iPF2alpha-VI is an isoprostane produced by non-enzymatic, free radical-induced peroxidative damage to membrane lipids. It is the most abundant isoprostane product that is formed during lipid peroxidation and is used as a biomarker for oxidative stress. 8,12-iso-iPF2alpha-VI is detected after CCl4-induced oxidative damage to hepatic tissue and has been found elevated in the urine, blood, and cerebrospinal fluid of patients with Alzheimer's disease.Formal Name: (12alpha)-5,9alpha,11alpha-trihydroxy-prosta-6E,14Z-dien-1-oic acid. CAS Number: 1445349-99-4. Synonyms: 8,12-iso-Isoprostane-F2alpha-VI, 12-iso-5,6E,14Z-PGF2alpha, 12-iso-5,6E,14Z-Prostaglandin F2alpha. Molecular Formula: C20H34O5. Formula Weight: 354.5. Purity: >95%. Formulation: (Request formulation change), A solution in acetonitrile. Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, Ethanol: 50 mg/ml, PBS (pH7.2): .5 mg/ml. SMILES: O[C@@H]1C[C@H](O)[C@H](/C=C/C(O)CCCC(O)=O)[C@@H]1C/C=C\CCCCC. InChi Code: InChI=1S/C20H34O5/c1-2-3-4-5-6-7-10-16-17(19(23)14-18(16)22)13-12-15(21)9-8-11-20(24)25/h6-7,12-13,15-19,21-23H,2-5,8-11,14H2,1H3,(H,24,25)/b7-6-,13-12+/t15?,16-,17+,18+,19-/m0/s1. InChi Key: RZCPXIZGLPAGEV-DCOIXEBESA-N.