6-trans Leukotriene B4

6-trans LTB4 is produced by the non-enzymatic hydrolysis of LTA4. Oxidative decomposition of cysteinyl-leukotrienes such as LTC4 in the presence of myeloperoxidase and hypochlorous acid can also produce 6-trans LTB4, but the physiologic importance of this mechanism is not clear. 6-trans LTB4 is relatively inactive compared to LTB4, but chemoattractant properties in neutrophils have been reported.Formal Name: 5S,12R-dihydroxy-6E,8E,10E,14Z-eicosatetraenoic acid. CAS Number: 71652-82-9. Synonyms: 6-trans LTB4, all-trans LTB4, 5(S),12(R)-DiHETE. Molecular Formula: C20H32O4. Formula Weight: 336.5. Purity: >97%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, Ethanol: 50 mg/ml, PBS pH 7.2: 1 mg/ml. lambdamax: 269 nm. SMILES: CCCCC/C=C\C[C@@H](O)/C=C/C=C/C=C/[C@@H](O)CCCC(O)=O. InChi Code: InChI=1S/C20H32O4/c1-2-3-4-5-6-9-13-18(21)14-10-7-8-11-15-19(22)16-12-17-20(23)24/h6-11,14-15,18-19,21-22H,2-5,12-13,16-17H2,1H3,(H,23,24)/b8-7+,9-6-,14-10+,15-11+/t18-,19-/m1/s1. InChi Key: VNYSSYRCGWBHLG-UKNWISKWSA-N.