4-oxo-2-Nonenal Alkyne

4-oxo-2-Nonenal (4-ONE, Cay-10185) is a product of lipid peroxidation that actively modifies histidine and lysine residues on proteins and causes protein cross-linking. It also modifies 2'-deoxyguanosine, further implicating lipid peroxidation in mutagenesis and carcinogenesis. 4-ONE alkyne is an alkyne-tagged electrophile that can be used as a probe to isolate and identify the reaction products of lipid peroxidation using click chemistry.Formal Name: 4-oxo-2E-Nonen-8-ynal. CAS Number: 1680193-58-1. Synonyms: 4-ONE Alkyne, Alkynyl 4-oxo-2-Nonenal, Click Tag(TM) 4-oxo-2-Nonenal Alkyne. Molecular Formula: C9H10O2. Formula Weight: 150.2. Purity: >98%. Formulation: (Request formulation change), A solution in methyl acetate. Solubility: DMF: 1 mg/ml, DMSO: 1 mg/ml, Ethanol: 10 mg/ml, PBS (pH 7.2): 5 mg/ml. lambdamax: 226 nm. SMILES: [H]C(/C=C/C(CCCC#C)=O)=O. InChi Code: InChI=1S/C9H10O2/c1-2-3-4-6-9(11)7-5-8-10/h1,5,7-8H,3-4,6H2/b7-5+. InChi Key: YSPMTKWXGONLQR-FNORWQNLSA-N.