(3beta,4beta,17beta)-17-(2-Pyridinylmethyl)androst-5-ene-3,4,17-triol

(3beta,4beta,17beta)-17-(2-Pyridinylmethyl)androst-5-ene-3,4,17-triol is a sterol lipid and derivative of 5-androstenetriol (Cay-35273). It is cytotoxic to MDA-MB-231 breast, PC3 prostate, HeLa cervical, and HT-29 colon cancer cells (IC50s = 9, 52.1, 26.6, and 8 µM, respectively) but not MRC-5 fibroblasts (IC50 = >100 µM).Formal Name: 17-(2-pyridinylmethyl)-androst-5-ene-3beta,4beta,17beta-triol. CAS Number: 1393651-00-7. Molecular Formula: C25H35NO3. Formula Weight: 397.6. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Soluble: >10 mg/ml, Ethanol: Soluble: >10 mg/ml, PBS (pH 7.2): Slightly soluble: 0.1-1 mg/ml. SMILES: C[C@@]12C3C(CC=C1[C@@H](O)[C@H](CC2)O)C4[C@](CC3)([C@](O)(CC5=NC=CC=C5)CC4)C. InChi Code: InChI=1S/C25H35NO3/c1-23-11-10-21(27)22(28)20(23)7-6-17-18(23)8-12-24(2)19(17)9-13-25(24,29)15-16-5-3-4-14-26-16/h3-5,7,14,17-19,21-22,27-29H,6,8-13,15H2,1-2H3/t17?,18?,19?,21-,22+,23+,24-,25+/m0/s1. InChi Key: VOJCRCXJCNNVLD-RZVICWFMSA-N.