3-Methylglutaconic Acid

3-Methylglutaconic acid (3-MGA) is a branched-chain organic acid and product of leucine catabolism. 3-MGA accumulates in 3-methylglutaconic aciduria, which is caused by an inborn error of leucine metabolism characterized by 3-MGA-CoA hydratase deficiency, leading to delayed development, hypoglycemia, metabolic acidosis, and neurological impairments.Formal Name: 3-methyl-2-pentenedioic acid. CAS Number: 5746-90-7. Synonyms: 3-MGA, beta-Methylglutaconic Acid, 3-MGC Acid, NSC 249232, FA 6:2,O2. Molecular Formula: C6H8O4. Formula Weight: 144.1. Purity: >95% (mixture of E/Z isomers). Formulation: (Request formulation change), A solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml, PBS (pH 7.2): 10 mg/ml. lambdamax: 213 nm. SMILES: O=C(C=C(CC(O)=O)C)O. InChi Code: InChI=1S/C6H8O4/c1-4(2-5(7)8)3-6(9)10/h2H,3H2,1H3,(H,7,8)(H,9,10). InChi Key: WKRBKYFIJPGYQC-UHFFFAOYSA-N.