25-hydroxy Vitamin D2

25-hydroxy Vitamin D2 is a metabolite of vitamin D2 (Cay-11791). It is formed from vitamin D2 by the cytochrome P450 (CYP) isoforms CYP2R1 and CYP27A1, which have 25-hydroxylase activity, and is bound to vitamin D binding protein (DBP) and albumin in the liver, then secreted into the bloodstream. 25-hydroxy Vitamin D2 is transported to the kidney, where it is preferentially 24-hydroxylated by CYP24A1 to produce 24,25-dihydroxy vitamin D2. It can also be hydroxylated by CYP27B1 to produce 1,25-dihydroxy vitamin D2. Serum levels of 25-hydroxy vitamin D2 have been used as a marker of vitamin D status.Formal Name: 4-methylene-3-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,2E,4S)-5-hydroxy-1,4,5-trimethyl-2-hexenyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-cyclohexanol. CAS Number: 21343-40-8. Synonyms: Ercalcidiol, 25-Hydroxyergocalciferol, 25(OH)-Vitamin D2. Molecular Formula: C28H44O2. Formula Weight: 412.7. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml, Ethanol: 20 mg/ml, Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml. lambdamax: 211, 264 nm. SMILES: C=C1CC[C@H](O)C/C1=C\C=C2CCC[C@@]3(C)[C@@]\2([H])CC[C@]3([H])[C@H](C)/C=C/[C@H](C)C(C)(O)C. InChi Code: InChI=1S/C28H44O2/c1-19-10-14-24(29)18-23(19)13-12-22-8-7-17-28(6)25(15-16-26(22)28)20(2)9-11-21(3)27(4,5)30/h9,11-13,20-21,24-26,29-30H,1,7-8,10,14-18H2,2-6H3/b11-9+,22-12-,23-13+/t20-,21+,24+,25-,26+,28-/m1/s1. InChi Key: KJKIIUAXZGLUND-UURWAHJLSA-N.