(±)17(18)-DiHETE

Eicosapentaenoic acid (EPA, Cay-90110) is an omega-3 fatty acid abundantly available in marine organisms. (±)17(18)-DiHETE is one of the major metabolites produced when eicosapentaenoic acid (EPA) is incubated with various rat tissue homogenates or cynomolgus monkey seminal vesicles. The route of production of (±)17(18)-DiHETE likely proceeds through cytochrome P450-catalyzed epoxidation at the omega-3 double bond followed by conversion to the vicinal diols by epoxide hydrolase. EPA is also metabolized preferentially by Gaeumannomyces graminis to (±)17(18)-DiHETE.Formal Name: (±)17,18-dihydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid. Synonyms: (±)17,18-dihydroxy-eicosa-5,8,11,14-Tetraenoic Acid. Molecular Formula: C20H32O4. Formula Weight: 336.5. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml, PBS (pH 7.2): .5 mg/ml. SMILES: CC[C@@H](O)[C@H](O)C/C=C\C/C=C\C/C=C\C/C=C\CCCC(O)=O. InChi Code: InChI=1S/C20H32O4/c1-2-18(21)19(22)16-14-12-10-8-6-4-3-5-7-9-11-13-15-17-20(23)24/h3,5-6,8-9,11-12,14,18-19,21-22H,2,4,7,10,13,15-17H2,1H3,(H,23,24)/b5-3-,8-6-,11-9-,14-12-/t18-,19-/m1/s1. InChi Key: XYDVGNAQQFWZEF-VXNZHGHESA-N.