16-Epiestriol

16-Epiestriol is a metabolite of the endogenous estrogen estrone (Cay-10006485). It is formed from estrone via a 16beta-hydroxy estrone intermediate by reduction of the C-17 ketone. 16-Epiestriol (200 µg/ml) inhibits the growth of carbapenem-resistant A. baumannii. It inhibits carrageenan-induced paw edema in rats when administered at a dose of 20 mg/kg. Unlike hydrocortisone, 16-epiestriol (240 µg/animal) does not increase plasma or liver glucose levels in adrenalectomized rats.Formal Name: (16beta,17beta)-estra-1,3,5(10)-triene-3,16,17-triol. CAS Number: 547-81-9. Synonyms: 16-epi Estriol, 16-EpiE3, 16beta-hydroxy-17alpha-Estradiol, NSC 26646. Molecular Formula: C18H24O3. Formula Weight: 288.4. Purity: >90%. Formulation: (Request formulation change), A solid. Solubility: Ethanol: 1 mg/ml. SMILES: C[C@@]12[C@](C[C@@H]([C@@H]2O)O)([H])[C@@]3([H])[C@@](CC1)([H])C4=CC=C(O)C=C4CC3. InChi Code: InChI=1S/C18H24O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-17,19-21H,2,4,6-7,9H2,1H3/t13-,14-,15+,16+,17+,18+/m1/s1. InChi Key: PROQIPRRNZUXQM-ZMSHIADSSA-N.