15(S)-HETE-d8 ethyl ester

15(S)-HETE-d8 ethyl ester is intended for use as an internal standard for the quantification of 15-HETE ethyl ester by GC- or LC-MS. 15(S)-HETE ethyl ester is an esterified form of 15(S)-HETE (Cay-34720), a major metabolite of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) via the 15-lipoxygenase pathway. 15(R)-HETE is produced by aspirin-acetylated COX-2 from arachidonic acid, the cytochrome P450 (CYP) isoform CYP2C9, or COX-1 in stimulated human mast cells. (±)15-HETE is produced by the non-enzymatic oxidation of arachidonic acid.Formal Name: 15(S)-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic-5,6,8,9,11,12,14,15-d8 acid, ethyl ester. Synonyms: 15(S)-Hydroxyeicosatetraenoic Acid-d8 ethyl ester. Molecular Formula: C22H28D8O3. Formula Weight: 356.6. Purity: >99% deuterated forms (d1-d8). Formulation: (Request formulation change), A solution in acetonitrile. Solubility: Acetonitrile: 1 mg/mL. lambdamax: 235 nm. SMILES: CCCCC[C@]([2H])(O)/C([2H])=C/C([2H])=C([2H])\C/C([2H])=C([2H])\C/C([2H])=C([2H])\CCCC(OCC)=O. InChi Code: InChI=1S/C22H36O3/c1-3-5-15-18-21(23)19-16-13-11-9-7-6-8-10-12-14-17-20-22(24)25-4-2/h6-7,10-13,16,19,21,23H,3-5,8-9,14-15,17-18,20H2,1-2H3/b7-6-,12-10-,13-11-,19-16+/t21-/m0/s1/i6D,7D,10D,11D,12D,13D,19D,21D. InChi Key: DXWNFRGRLVMUIG-QYYQKCNUSA-N.