11-dehydro Thromboxane B2

Thromboxane B2 (TXB2) is released in substantial quantities from aggregating platelets and metabolized during circulation to 11-dehydro TXB2 and 2,3-dinor TXB2. 11-dehydro TXB2 is one of the main plasma metabolites of TXB2 and can be used as a marker for in vivo TXA2 synthesis. The mean plasma level in human males is 0.9-4.3 pg/ml and the half life is 45-60 minutes. Urinary concentrations of 11-dehydro TXB2 are approximately 30-70 ng/mmol creatinine.Formal Name: 9alpha,15S-dihydroxy-11-oxothromba-5Z,13E-dien-1-oic acid. CAS Number: 67910-12-7. Synonyms: 11-dehydro TXB2, 11-keto TXB2. Molecular Formula: C20H32O6. Formula Weight: 368.5. Purity: >98%. Formulation: (Request formulation change), A solution in methyl acetate. Solubility: DMF: 50 mg/ml (from TXB2), DMSO: 25 mg/ml (from TXB2), Ethanol: 100 mg/ml (from TXB2), PBS pH 7.2: 100 µg/ml (from TXB2). SMILES: CCCCC[C@H](O)/C=C/[C@H]1OC(C[C@H](O)[C@@H]1C/C=C\CCCC(O)=O)=O. InChi Code: InChI=1S/C20H32O6/c1-2-3-6-9-15(21)12-13-18-16(17(22)14-20(25)26-18)10-7-4-5-8-11-19(23)24/h4,7,12-13,15-18,21-22H,2-3,5-6,8-11,14H2,1H3,(H,23,24)/b7-4-,13-12+/t15-,16-,17-,18+/m0/s1. InChi Key: KJYIVXDPWBUJBQ-UHHGALCXSA-N.