11-dehydro-2,3-dinor Thromboxane B2-d9

11-dehydro-2,3-dinor Thromboxane B2-d9 (11-dehydro-2,3-dinor TXB2-d9) is intended for use as an internal standard for the quantification of 11-dehydro-2,3-dinor TXB2 (Cay-19510) by GC- or LC-MS. 11-dehydro-2,3-dinor TXB2 is a metabolite of the TXA2 inactive metabolite TXB2 (Cay-19030). It is formed from TXB2 by cytosolic aldehyde dehydrogenase (ALDH) and beta-oxidation. Levels of 11-dehydro-2,3-dinor TXB2 are increased 5.2-fold in a surgery-induced rat model of tendon overuse.Formal Name: (Z)-5-((2R,3S,4S)-4-hydroxy-2-((S,E)-3-hydroxyoct-1-en-1-yl-5,5,6,6,7,7,8,8,8-d9)-6-oxotetrahydro-2H-pyran-3-yl)pent-3-enoic acid. Synonyms: 11-dehydro-2,3-dinor TXB2-d9. Molecular Formula: C18H19D9O6. Formula Weight: 349.5. Purity: >99% deuterated forms (d1-d9). Formulation: (Request formulation change), A solution in methyl acetate. Solubility: DMF: 50 mg/ml, DMSO: 25 mg/ml, Ethanol: 100 mg/ml, Methyl Acetate: 1 mg/ml, PBS (pH 7.2): 100 µg/ml. SMILES: O[C@@H]1[C@H](C/C=C\CC(O)=O)[C@@H](/C=C/[C@@H](O)CC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])OC(C1)=O. InChi Code: InChI=1S/C18H28O6/c1-2-3-4-7-13(19)10-11-16-14(8-5-6-9-17(21)22)15(20)12-18(23)24-16/h5-6,10-11,13-16,19-20H,2-4,7-9,12H2,1H3,(H,21,22)/b6-5-,11-10+/t13-,14-,15-,16+/m0/s1/i1D3,2D2,3D2,4D2. InChi Key: PJAAKFHMQLYVGV-PAYANANYSA-N.