1-Palmitoyl-2-Oleoyl-sn-glycero-3-PE

1-Palmitoyl-2-oleoyl-sn-glycero-3-PE (1,2-POPE) is a phospholipid that contains palmitic acid (Cay-10006627) and oleic acid (Cay-90260, Cay-24659) at the sn-1 and sn-2 positions, respectively. It is a major component of E. coli lipid bilayers, and vesicles composed of 1,2-POPE can be disrupted by polycationic antimicrobials. 1,2-POPE has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for spleen- and liver-specific targeting in mice.Formal Name: 9Z-octadecenoic acid, (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-2-[(1-oxohexadecyl)oxy]ethyl ester. CAS Number: 26662-94-2. Synonyms: 1-Palmitoyl-2-Oleoyl-sn-glycero-3-Phosphatidylethanolamine, 1-Palmitoyl-2-Oleoyl-sn-glycero-3-Phosphoethanolamine, 16:0-18:1 PE, PE(16:0/18:1), 1,2-POPE. Molecular Formula: C39H76NO8P. Formula Weight: 718.0. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Chloroform: 100 mg/ml. SMILES: O=C(CCCCCCCCCCCCCCC)OC[C@@H](OC(CCCCCCC/C=C\CCCCCCCC)=O)COP(OCC[NH3+])([O-])=O. InChi Code: InChI=1S/C39H76NO8P/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-39(42)48-37(36-47-49(43,44)46-34-33-40)35-45-38(41)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h17-18,37H,3-16,19-36,40H2,1-2H3,(H,43,44)/b18-17-/t37-/m1/s1. InChi Key: FHQVHHIBKUMWTI-OTMQOFQLSA-N. Side Chain Carbon Sum: 34:1.