1-Palmitoyl-2-hydroxy-sn-glycero-3-PC

1-Palmitoyl-2-hydroxy-sn-glycero-3-PC
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay10172-25 25 mg -

5 - 10 Werktage*

49,00 €
Cay10172-50 50 mg -

5 - 10 Werktage*

93,00 €
Cay10172-100 100 mg -

5 - 10 Werktage*

147,00 €
Cay10172-500 500 mg -

5 - 10 Werktage*

244,00 €
 
1-Palmitoyl-2-hydroxy-sn-glycero-3-PC is the ubiquitous lipid species generated following... mehr
Produktinformationen "1-Palmitoyl-2-hydroxy-sn-glycero-3-PC"
1-Palmitoyl-2-hydroxy-sn-glycero-3-PC is the ubiquitous lipid species generated following phospholipase A2 (PLA2) hydrolysis of phosphatidylcholine. It increases the production of reactive oxygen species (ROS) and decreases superoxide dismutase (SOD) and endothelial nitric oxide synthase (eNOS) protein levels and phosphorylation of ERK1/2 in human umbilical vein endothelial cells (HUVECs) when used at a concentration of 125 µM. 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC potentiates the secretion of IL-6, IL-1beta, IL-12, and TNF-alpha in LPS-stimulated M1 macrophages, but has no effect on CD163, CD206, CD36, or IL-10 in LPS-stimulated M2 macrophages when used at concentrations of 0.3 and 1.0 µM. It increases TGF-beta1 production and enhances Foxp3 protein levels in Treg cells in isolated human peripheral blood when used at a concentration of 10 µM. 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC enhances neutrophil function, bacterial clearance, and survival in mouse models of sepsis when administered at a dose of 10 mg/kg. Formal Name: 1-hexadecanoyl-sn-glycerol-3-phosphorylcholine. CAS Number: 17364-16-8. Synonyms: 1-Hexadecanoyl-sn-glycero-3-Phosphatidylcholine, 1-Hexadecanoyl-sn-glycero-3-Phosphocholine, 1-Palmitoyl-sn-glycero-3-Phosphocholine, PC(16:0/0:0), 16:0/0:0-PC. Molecular Formula: C24H50NO7P. Formula Weight: 495.6. Purity: >98%. Formulation: A crystalline solid. Solubility: PBS (pH 7.2): 2 mg/ml. SMILES: CCCCCCCCCCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)OCC[N](C)(C)C. InChi Code: InChI=1S/C24H50NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-24(27)30-21-23(26)22-32-33(28,29)31-20-19-25(2,3)4/h23,26H,5-22H2,1-4H3/t23-/m1/s1. InChi Key: ASWBNKHCZGQVJV-HSZRJFAPSA-N. Side Chain Carbon Sum: 16:0.
Schlagworte: 16:0/0:0-PC, 1-Hexadecanoyl-sn-glycero-3-Phosphatidylcholine, 1-Hexadecanoyl-sn-glycero-3-Phosphocholine, 1-Palmitoyl-sn-glycero-3-Phosphocholine, PC(16:0/0:0), 1-hexadecanoyl-sn-glycerol-3-phosphorylcholine
Hersteller: Cayman Chemical
Hersteller-Nr: 10172

Eigenschaften

Anwendung: Bioactive lipid assays
MW: 495.6 D
Formel: C24H50NO7P
Reinheit: >98%
Format: Crystalline Solid

Datenbank Information

CAS : 17364-16-8| Finde Alternativen

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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