1-Arachidonoyl-d8-rac-glycerol

1-Arachidonoyl-d8-rac-glycerol (1-AG-d8) is intended for use as an internal standard for the quantification of 1-AG (Cay-62150) by GC- or LC-MS. 1-AG is a weak cannabinoid (CB1) receptor agonist and may have other pharmacologic properties. 1-AG is an isomer of 2-AG. 2-AG is chemically unstable and undergoes rapid isomerization to 1-AG (synonymous with 1(3)-AG) both in vitro and in vivo. 1-AG is a frequent contaminant in synthetic 2-AG preparations, and can markedly reduce their cannabinergic potency.Formal Name: 5Z,8Z,11Z,14Z-eicosatetraenoic-5,6,8,9,11,12,14,15-d8 acid, 2,3-dihydroxypropyl ester. CAS Number: 2692624-29-4. Synonyms: 1-AG-d8. Molecular Formula: C23H30D8O4. Formula Weight: 386.6. Purity: >99% deuterated forms (d1-d8). Formulation: (Request formulation change), A solution in acetonitrile. Solubility: DMSO: 2 mg/ml, Ethanol: miscible, PBS (pH 7.2): 0.1 mg/ml. SMILES: O=C(OCC(CO)O)CCC/C([2H])=C([2H])\C/C([2H])=C([2H])\C/C([2H])=C([2H])\C/C([2H])=C([2H])\CCCCC. InChi Code: InChI=1S/C23H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(26)27-21-22(25)20-24/h6-7,9-10,12-13,15-16,22,24-25H,2-5,8,11,14,17-21H2,1H3/b7-6-,10-9-,13-12-,16-15-/i6D,7D,9D,10D,12D,13D,15D,16D. InChi Key: DCPCOKIYJYGMDN-FBFLGLDDSA-N. Side Chain Carbon Sum: 20:4.