1,2-Dioleoyl-sn-glycero-3-PE

1,2-Dioleoyl-sn-glycero-3-PE (1,2-DOPE) is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions. The compound features the same diacylglycerol stereochemistry as that of the natural compound. 1,2-DOPE can be used as an emulsifier to facilitate DNA-liposome complex transport across membranes. It is used in combination with cationic phospholipids to increase efficiency during DNA transfection studies as a non-viral method of gene delivery.Formal Name: 1,2-dioleoyl-sn-glycero-3-phosphatidylethanolamine. CAS Number: 4004-05-1. Synonyms: 1,2-Dioleoyl-sn-glycero-3-Phosphoethanolamine, 1,2-DOPE. Molecular Formula: C41H78NO8P. Formula Weight: 744.1. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: Chloroform: 3.3 mg/ml. SMILES: CCCCCCCC/C=C\CCCCCCCC(O[C@@H](COP(OCC[NH3+])([O-])=O)COC(CCCCCCC/C=C\CCCCCCCC)=O)=O. InChi Code: InChI=1S/C41H78NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(43)47-37-39(38-49-51(45,46)48-36-35-42)50-41(44)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h17-20,39H,3-16,21-38,42H2,1-2H3,(H,45,46)/b19-17-,20-18-/t39-/m1/s1. InChi Key: MWRBNPKJOOWZPW-NYVOMTAGSA-N. Origin: Synthetic. Side Chain Carbon Sum: 36:2.