1,2-Didocosahexaenoyl-sn-glycero-3-PC

1,2-Didocosahexaenoyl-sn-glycero-3-PC is a phospholipid that contains docosahexaenoic acid (Cay-90310, Cay-17950) at the sn-1 and sn-2 positions. It has been used in the formation of polyunsaturated endoplasmic reticulum-targeting liposomes (PERLs) that reduce cellular cholesterol levels in human peripheral blood mononuclear cells (PBMCs) and decrease the secretion of HIV-1 particles in PBMCs infected with HIV-1LAI. It has been used as a component of lipid monolayers and small unilamellar vesicles to study the effect of phospholipid composition on membrane fluidity.Formal Name: (7R,13Z,16Z,19Z,22Z,25Z,28Z)-4-hydroxy-N,N,N-trimethyl-10-oxo-7-[[(4Z,7Z,10Z,13Z,16Z,19Z)-1-oxo-4,7,10,13,16,19-docosahexaenyl]oxy]-3,5,9-trioxa-4-phosphahentriaconta-13,16,19,22,25,28-hexaen-1-aminium, inner salt, 4-oxide. CAS Number: 99296-81-8. Synonyms: 1,2-Didocosahexaenoyl PC, 1,2-Didocosahexaenoyl-sn-glycero-3-Phosphocholine, 1,2-Didocosahexaenoin-sn-glycero-3-Phosphatidylcholine, PC(22:6/22:6), 22:6/22:6-PC. Molecular Formula: C52H80NO8P. Formula Weight: 878.2. Purity: >95%. Formulation: (Request formulation change), A solution in chloroform. Solubility: Chloroform: Soluble. SMILES: O=P(OCC[N+](C)(C)C)([O-])OC[C@H](OC(CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC)=O)COC(CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC)=O. InChi Code: InChI=1S/C52H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-40-42-44-51(54)58-48-50(49-60-62(56,57)59-47-46-53(3,4)5)61-52(55)45-43-41-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h8-11,14-17,20-23,26-29,32-35,38-41,50H,6-7,12-13,18. InChi Key: XLKQWAMTMYIQMG-SVUPRYTISA-N.