Psoralen-PEG3-Biotin

Molecular weight: 688.79. Psoralen-PEG3-Biotin is a photoactivatable reagent for biotinylating DNA or RNA. Psoralen-PEG3-Biotin has a psoralen group that can intercalate into double-stranded DNA or RNA and form covalent bonds with thymine and other pyrimidine bases when exposed to UV light (around 350 nm). Psoralen-PEG3-Biotin contains a polyethylene glycol (PEG) spacer arm that enhances the solubility and accessibility of the biotin moiety. Psoralen-PEG3-Biotin is used for selective labeling of cell surface proteins, biotinylation of hyaluronan, labeling of endotoxin for receptor binding studies, and crosslinking of nucleic acids for genomic investigations. It can also be used to study nucleic acid and protein interactions.