Coumarin hydrazine

Coumarin hydrazine is an aromatic hydrazine-containing fluorophore that reacts with aldehydes or ketones for fluorescent labeling. At neutral pH, coumarin hydrazine reacts faster with aldehydes than coumarin hydrazide to form hydrazones. Coumarin hydrazine acts as a fluorogenic sensor in live cells to detect carbonylated biomolecules that occur following oxidative stress. It displays an excitation maximum of 365 nm, produces a red shift in emission from approximately 430-550 nm upon hydrozone formation, and displays a large Stokes shift of approximately 195 nm.Formal Name: 7-hydrazinyl-4-methyl-2H-1-benzopyran-2-one. CAS Number: 113707-87-2. Synonyms: BzCH, CH-1, 7-hydrazino-4-methyl Coumarin. Molecular Formula: C10H10N2O2. Formula Weight: 190.2. Purity: >90%. Emission: 430-550 nm. Excitation: 365 nm. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 14 mg/ ml, DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml, DMSO: 10 mg/ml, Ethanol: 1 mg/ml. lambdamax: 222, 324 nm. SMILES: O=C(C=C1C)OC2=C1C=CC(NN)=C2. InChi Code: InChI=1S/C10H10N2O2/c1-6-4-10(13)14-9-5-7(12-11)2-3-8(6)9/h2-5,12H,11H2,1H3. InChi Key: ZGALTRTXIDNBJL-UHFFFAOYSA-N.