Cal-670(TM), potassium salt

Calcium measurement is critical for numerous biological investigations. Fluorescent probes that show spectral responses upon binding calcium have enabled researchers to investigate changes in intracellular free calcium concentrations by using fluorescence microscopy, flow cytometry, fluorescence spectroscopy and fluorescence microplate readers. Cal-670(TM) is a near infrared (NIR) calcium indicator with maximum emission at ~675 nm. It can be well excited with the red lasers at 633 nm or 647 nm with a moderate calcium affinity of Kd ~853 nM. Cal-670(TM) is one of the very few calcium indicators that can be potentially used for in vivo imaging since it has a NIR fluorescence.