Biotin-azide

Biotin-azide is a form of biotin with a terminal azide group. It is used to add biotin to other molecules that bear either an alkyne group, through click chemistry, or a phosphine group, using Staudinger ligation. Biotin-azide has been commonly used to biotin-tag alkynylated lipids, particularly those associated with proteins through post-translational modification. It can also be used to biotin-tag proteins, lipids, carbohydrates, and nucleic acids that have been modified with alkyne or phosphine groups.Formal Name: (3aS,4S,6aR)-N-(3-azidopropyl)hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide. CAS Number: 908007-17-0. Synonyms: Azido-biotin, Click Tag(TM) Biotin-azide. Molecular Formula: C13H22N6O2S. Formula Weight: 326.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 5 mg/ml, DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml, PBS (pH 7.2): Sparingly ( < 100 µg/ml). SMILES: O=C(N1)N[C@]([C@]1([H])CS2)([H])[C@@H]2CCCCC(NCCCN=[N+]=[N-])=O. InChi Code: InChI=1S/C13H22N6O2S/c14-19-16-7-3-6-15-11(20)5-2-1-4-10-12-9(8-22-10)17-13(21)18-12/h9-10,12H,1-8H2,(H,15,20)(H2,17,18,21)/t9-,10-,12-/m0/s1. InChi Key: SWODDJWJUGOAQB-NHCYSSNCSA-N.