3,3'-Dihexyloxacarbocyanine (iodide)

3,3'-Dihexyloxacarbocyanine (DiOC6(3)) is a lipophilic fluorescent dye with excitation/emission spectra of 484/501 nm, respectively. At high concentrations, DiOC6(3) accumulates in the endoplasmic reticulum (ER) and has been used to visualize ER in moss, yeast, and muscle cells. At low concentrations, DiOC6(3) accumulates in mitochondria and has been used to assess mitochondrial dislocations, fusion, and fission in living cells, as well as to visualize cellular apoptosis. DiOC6(3) can also be used to assess cell membrane potential, as depolarization directly correlates with increased fluorescence. DiOC6(3) photoexcitation inactivates intracellular organelle movement and inhibits microtubule polymerization in vitro.Formal Name: 3-hexyl-2-[3-(3-hexyl-2(3H)-benzoxazolylidene)-1-propen-1-yl]-benzoxazolium, iodide. CAS Number: 53213-82-4. Synonyms: DiOC6(3), NK 2280. Molecular Formula: C29H37N2O2 . I. Formula Weight: 572.5. Purity: >98%. Emission: 501 nm. Excitation: 484 nm. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml. lambdamax: 486 nm. SMILES: CCCCCCN1C2=CC=CC=C2O/C1=C\C=C\C3=[N+](CCCCCC)C4=C(C=CC=C4)O3.[I-]. InChi Code: InChI=1S/C29H37N2O2.HI/c1-3-5-7-13-22-30-24-16-9-11-18-26(24)32-28(30)20-15-21-29-31(23-14-8-6-4-2)25-17-10-12-19-27(25)33-29,/h9-12,15-21H,3-8,13-14,22-23H2,1-2H3,1H/q+1,/p-1. InChi Key: XVLXYDXJEKLXHN-UHFFFAOYSA-M.