YW1159

YW1159 is an inhibitor of Wnt signaling with an IC50 value of 1.2 nM in a reporter assay. It is not cytotoxic to HEK293 cells following incubations of up to 24 hours but cell viability is decreased in a concentration-dependent manner after 72 hours.Formal Name: 1-(2-fluorophenyl)-5-methyl-N-2-quinolinyl-1H-1,2,3-triazole-4-carboxamide. CAS Number: 2131223-69-1. Synonyms: Compound 3d. Molecular Formula: C19H14FN5O. Formula Weight: 347.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: Chloroform: 30 mg/ml, DMF: 5 mg/ml, DMF:PBS (pH 7.2) (1:3): 0.25 mg/ml. lambdamax: 257, 318, 332 nm. SMILES: O=C(C1=C(C)N(C2=C(F)C=CC=C2)N=N1)NC3=CC=C(C=CC=C4)C4=N3. InChi Code: InChI=1S/C19H14FN5O/c1-12-18(23-24-25(12)16-9-5-3-7-14(16)20)19(26)22-17-11-10-13-6-2-4-8-15(13)21-17/h2-11H,1H3,(H,21,22,26). InChi Key: PNGUNLPOXKPCPK-UHFFFAOYSA-N.