Xite(TM) Red beta-D-galactopyranoside

Xite(TM) Red beta-D-galactopyranoside provides a simple and sensitive tool to detect beta-galactosidase (beta-gal) activity. Compared to the existing red beta-galactosidase substrates (e.g., the commonly used resorufin beta-D-galactopyranoside), it has much better cell permeability. Xite(TM) Red beta-D-galactopyranoside provides a simple and sensitive tool to detect beta-galactosidase activity. Xite(TM) Red beta-D-galactopyranoside might be used as a simple tool for measuring cellular senescence in cells since beta-gal has been identified as a reliable marker for cellular senescence. Xite(TM) Red beta-D-galactopyranoside enters readily cells where it gets cleaved by beta-gal, producing Xite(TM) Red, a strongly fluorescent product. The strongly fluorescent Xite(TM) Red is well retained in cells, making it easy to be detected with a flow cytometer and fluorescence microscope. In addition, Xite(TM) Red beta-D-galactopyranoside is fixable. The red fluorescence generated by Xite(TM) Red beta-D-galactopyranoside can be readily combined with other color fluorescent probes such as DAPI or GFP for multicolor fluorescence analysis.