Xanthine

Xanthine is a purine base and intermediate in the biosynthesis of uric acid (Cay-16219). It is formed during mammalian purine catabolism in the liver via oxidation of hypoxanthine (Cay-22254) by xanthine oxidase (XO), which also oxidizes xanthine to produce uric acid. Xanthine is also formed from guanine, xanthosine, or hypoxanthine during purine catabolism in plants. It has been found in a variety of commercial foodstuffs, including beer yeast, mushrooms, vegetables, fish, and beef. Urinary xanthine levels are decreased in patients with primary gout. Xanthine has also been used in the synthesis of xanthine derivatives that have anticancer or anti-inflammatory activities in vitro.Formal Name: 3,9-dihydro-1H-purine-2,6-dione. CAS Number: 69-89-6. Synonyms: 2,6-Dihydroxypurine, NSC 14664. Molecular Formula: C5H4N4O2. Formula Weight: 152.1. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 1 mg/ml, PBS (pH 7.2): 1 mg/ml. lambdamax: 268 nm. SMILES: O=C1NC(C2=C(N1)N=CN2)=O. InChi Code: InChI=1S/C5H4N4O2/c10-4-2-3(7-1-6-2)8-5(11)9-4/h1H,(H3,6,7,8,9,10,11). InChi Key: LRFVTYWOQMYALW-UHFFFAOYSA-N.