VEGFR-2-IN-64

Description: VEGFR-2-IN-64 (Compound 28) is an inhibitor of VEGFR2 with an IC50 of 27.8 nM. It suppresses the proliferation of cancer cells A549, T-47D, and Caco-2, exhibits anti-migration and anti-colony formation activities in T-47D cells, and induces apoptosis in T-47D cells. Target: Apoptosis, VEGFR. Smiles: CCCCCCCCCC CCCCCCCCN1C=C(N=N1)COC(=O)C2=CC(=CC(=C2)C(=O)OCC3=CN(N=N3)CCCCCCCCCCCCCCCCCC)C(=O)OCC4=CN(N=N4)CCCCCCCCCCCCCCCCCC