Unifiram

Description: Unifiram is a cognition-enhancer. Unifiram induces a long-lasting increase in the amplitude of field excitatory postsynaptic potentials (fEPSPs) in the rat hippocampal CA1 region (EC50= 27 nM) and increases acetylcholine (ACh) release in the rat cerebral cortex. Target: Others. Smiles: Fc1ccc(cc1)S(=O)(=O)N1CCN2C(CCC2=O)C1. References: Romanelli MN, et al. Pharmacological characterization of DM232 (unifiram) and DM235 (sunifiram), new potent cognition enhancers. CNS Drug Rev. 2006 Spring,12(1):39-52.