trans-Vaccenic Acid

trans-Vaccenic acid is an omega-7 fatty acid that has been found in bovine milk fats. Dietary administration of trans-vaccenic acid (1% w/w) reduces total body fat, mesenteric fat, and adipocyte size, increases inguinal fat mass, and decreases intestinal and hepatic triglyceride secretion in a rat model of obesity with features of metabolic syndrome. It decreases hepatocellular ballooning and steatosis, markers of non-alcoholic fatty liver disease (NAFLD), in the same model. Dietary administration of a butter enriched with trans-vaccenic acid decreases serum cholesterol levels and the formation of aortic atherosclerotic lesions in Ldlr-/- mice.Formal Name: 11E-octadecenoic acid. CAS Number: 693-72-1. Synonyms: C18:1(11E), C18:1 n-7, FA 18:1, trans-11-Octadecenoic acid. Molecular Formula: C18H34O2. Formula Weight: 282.5. Purity: >95%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 100 mg/ml, Ethanol:PBS (pH 7.2) (1:1): 0.5 mg/ml. SMILES: OC(CCCCCCCCC/C=C/CCCCCC)=O. InChi Code: InChI=1S/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h7-8H,2-6,9-17H2,1H3,(H,19,20)/b8-7+. InChi Key: UWHZIFQPPBDJPM-BQYQJAHWSA-N. Side Chain Carbon Sum: 18:1.