trans-Clovamide

trans-Clovamide is a naturally occurring caffeoyl conjugate identified in the antioxidant polyphenolic fraction of cocoa (T. cacao L.). It has antioxidant and antiradical properties and has shown neuroprotective effects (EC50s = 0.9-3.7 µM) in several in vitro models of neuronal death.Formal Name: N-[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]-3-hydroxy-L-tyrosine. CAS Number: 53755-02-5. Synonyms: N-[3',4'-Dihydroxy-(E)-cinnamoyl]-3-hydroxy-L-tyrosine, N-trans-Caffeoyl-L-DOPA. Molecular Formula: C18H17NO7. Formula Weight: 359.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 25 mg/ml, Ethanol: 0.3 mg/ml, PBS (pH 7.2): 10 mg/ml. lambdamax: 219, 290, 324 nm. SMILES: OC1=CC=C(/C=C/C(N[C@H](C(O)=O)CC2=CC=C(O)C(O)=C2)=O)C=C1O. InChi Code: InChI=1S/C18H17NO7/c20-13-4-1-10(8-15(13)22)3-6-17(24)19-12(18(25)26)7-11-2-5-14(21)16(23)9-11/h1-6,8-9,12,20-23H,7H2,(H,19,24)(H,25,26)/b6-3+/t12-/m0/s1. InChi Key: GPZFXSWMDFBRGS-UXONFWTHSA-N. Origin: Synthetic.