TP-004

TP-004 is an inhibitor of methionyl aminopeptidase 2 (METAP2, IC50 = 6 nM).Formal Name: 1-[4-methyl-5-[6-(trifluoromethyl)-1H-indazol-4-yl]-2-pyrimidinyl]-3R-pyrrolidinol. CAS Number: 1454299-21-8. Molecular Formula: C17H16F3N5O. Formula Weight: 363.3. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Acetonitrile: Slightly soluble: 0.1-1 mg/ml, Methanol: Sparingly soluble: 1-10 mg/ml. SMILES: FC(F)(C1=CC(C2=CN=C(N=C2C)N3CC[C@@H](O)C3)=C4C=NNC4=C1)F. InChi Code: InChI=1S/C17H16F3N5O/c1-9-13(6-21-16(23-9)25-3-2-11(26)8-25)12-4-10(17(18,19)20)5-15-14(12)7-22-24-15/h4-7,11,26H,2-3,8H2,1H3,(H,22,24)/t11-/m1/s1. InChi Key: BNTAEJNPQLMGDJ-LLVKDONJSA-N.