Tetrapeptide GEKG (trifluoroacetate salt)

Tetrapeptide GEKG is a peptide corresponding to amino acids 167-170 of human collagen IV. It increases the expression of the extracellular matrix (ECM) factors collagen I, hyaluronan synthase 1, and fibronectin in primary human dermal fibroblasts (HDFs). Tetrapeptide GEKG (1 and 10 ppm) induces the secretion of procollagen from HDFs. It also increases the viability of HDFs with a synergistic effect when used in combination with injectable platelet-rich fibrin (i-PRF). Formulations containing tetrapeptide GEKG have been used in cosmetics.. SMILES: O=C(CN)N[C@H](C(N[C@H](C(NCC(O)=O)=O)CCCCN)=O)CCC(O)=O.OC(C(F)(F)F)=O. InChi Code: InChI=1S/C15H27N5O7.C2HF3O2/c16-6-2-1-3-9(14(26)18-8-13(24)25)20-15(27)10(4-5-12(22)23)19-11(21)7-17,3-2(4,5)1(6)7/h9-10H,1-8,16-17H2,(H,18,26)(H,19,21)(H,20,27)(H,22,23)(H,24,25),(H,6,7)/t9-,10-,/m0./s1. InChi Key: YLYKLDPEQOQQMT-IYPAPVHQSA-N