Tenellin

Tenellin is a fungal metabolite that has been found in Beauveria. It inhibits Mg2+-, Ca2+-, and Na+/K+-ATPase activities in equine erythrocytes by 51, 57, and 74%, respectively, when used at a concentration of 200 µg/ml. Tenellin is cytotoxic to Sf9 and Sf21 insect cells with 50% cytotoxic concentration (CC50) values of­ 4.84 and 11.95 µM, respectively.Formal Name: 3-[(2E,4E,6R)-4,6-dimethyl-1-oxo-2,4-octadien-1-yl]-1,4-dihydroxy-5-(4-hydroxyphenyl)-2(1H)-pyridinone. CAS Number: 53823-15-7. Molecular Formula: C21H23NO5. Formula Weight: 369.4. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMF: soluble, DMSO: soluble, Ethanol: soluble, Methanol: soluble. SMILES: OC1=CC=C(C(C(O)=C2C(/C=C/C(C)=C/[C@H](C)CC)=O)=CN(O)C2=O)C=C1. InChi Code: InChI=1S/C21H23NO5/c1-4-13(2)11-14(3)5-10-18(24)19-20(25)17(12-22(27)21(19)26)15-6-8-16(23)9-7-15/h5-13,23,25,27H,4H2,1-3H3/b10-5+,14-11+/t13-/m1/s1. InChi Key: YELFBSBOFKWHSL-UCFWAISOSA-N. Origin: Fungus/Beauveria sp..