TEMPONE

2,2,6,6-Tetramethylpiperidin-1-oxyl (TEMPO) is a stable radical that will react with reactive oxygen species (ROS). This conversion, followed by ESR, provides an indirect way to monitor ROS production in biological systems. TEMPONE is the 4-oxo derivative of TEMPO. In addition to possible uses as a spin trap, this nitroxyl radical can be used in hydrogen transfer experiments and as a polarizing agent in dynamic nuclear polarization NMR spectroscopy. TEMPONE and other nitroxyl radicals have also been shown to reduce mean arterial pressure in spontaneously hypertensive rats when administered intravenously.Formal Name: 2,2,6,6-tetramethyl-4-oxo-1-piperidinyloxy. CAS Number: 2896-70-0. Synonyms: 4-oxo-TEMPO, Triacetoneamine nitroxide. Molecular Formula: C9H16NO2. Formula Weight: 170.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml, PBS (pH 7.2): 10 mg/ml. lambdamax: 236 nm. SMILES: O=C1CC(C)(C)N([O])C(C)(C)C1. InChi Code: InChI=1S/C9H16NO2/c1-8(2)5-7(11)6-9(3,4)10(8)12/h5-6H2,1-4H3. InChi Key: WSGDRFHJFJRSFY-UHFFFAOYSA-N.