TD139

Description: TD139 is an inhaled galectin-3 inhibitor with a dissociation constant (Kd) of 14 nM. Target: Galectin. Smiles: OC[C@H]1O[C@@H](S[C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2cccc(F)c2)[C@H](O)[C@H]([C@H]1O)n1cc(nn1)-c1cccc(F)c1. References: Mackinnon AC, et al. Regulation of transforming growth factor-beta1-driven lung fibrosis by galectin-3. Am J Respir Crit Care Med. 2012 Mar 1,185(5):537-46.