TCO-PEG11-TCO

Description: TCO-PEG11-TCO is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. Target: Others. Smiles: O=C(O[C@H]1CCC/C([H])=C/CC1)NCCOCCOCCO CCOCCOCCOC COCCOCCOCC OCCOCCNC(O[C@H]2CCC/C([H])=C/CC2)=O. References: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct,36:553-562