Taurine

Taurine is a sulfur-containing amino acid produced endogenously and also ingested in the diet. It is ubiquitously present in most cells and has diverse biological activities, including antioxidative, anticancer, cardioprotective, and neuroprotective properties. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH, Cay-14805) radicals when used at concentrations ranging from 125 to 1,000 µg/ml and decreases the viability of MCF-7 and MDA-MB-231 human breast cancer cells. It prevents left ventricular dysfunction in the mdx mouse model of late-stage Duchenne muscular dystrophy when administered at a dose of 1 g/kg per day for six months. Taurine (100 µM) prevents neurotoxicity induced by amyloid-beta (Abeta) or the glutamate receptor agonists glutamate, NMDA (Cay-14581), or kainic acid (Cay-78050) in chick embryonic retinal neurons, an effect that can be blocked by the GABAA receptor antagonist picrotoxin (Cay-20771).Formal Name: 2-amino-ethanesulfonic acid. CAS Number: 107-35-7. Synonyms: beta-Aminoethylsulfonic Acid, NSC 32428. Molecular Formula: C2H7NO3S. Formula Weight: 125.1. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: Water: 5 mg/ml. SMILES: OS(CCN)(=O)=O. InChi Code: InChI=1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6). InChi Key: XOAAWQZATWQOTB-UHFFFAOYSA-N.