Tanomastat

Description: Tanomastat is an orally bioavailable and non-peptidic biphenyl matrix metalloproteinases inhibitor. For MMP-2, MMP-3, MMP-9, MMP-13 the Ki values are 11, 143, 301, and 1470 nM respectively. Target: MMP. Smiles: C(C[C@H](CSC1=CC=CC=C1)C(O)=O)(=O)C2=CC=C(C=C2)C3=CC=C(Cl)C=C3. References: Leung D, et al. Protease inhibitors: current status and future prospects. J Med Chem. 2000 Feb 10,43(3):305-41.