Talarozole

Artikelnummer	Größe	Manual	SDB	Lieferzeit	Preis
Cay42372-5	5 mg	-	-	6 - 10 Werktage*	142,00 €
Cay42372-10	10 mg	-	-	6 - 10 Werktage*	242,00 €
Cay42372-25	25 mg	-	-	6 - 10 Werktage*	423,00 €
Cay42372-50	50 mg	-	-	6 - 10 Werktage*	564,00 €

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A CYP26 inhibitor (IC50 = 0.004 µM), selective for CYP26 over CYP2A1, CYP2C11, CYP17, and CYP19... mehr

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Produktinformationen "Talarozole"

A CYP26 inhibitor (IC50 = 0.004 µM), selective for CYP26 over CYP2A1, CYP2C11, CYP17, and CYP19 (IC50s = 9.1, 7.2, 2.6, and 1.3 µM, respectively), increases the levels of all-trans retinoic acid in plasma, skin, liver, fat, kidneys, and spleen in rats at 2.5 mg/kg, inhibits estrogen-induced vaginal keratinization in ovariectomized rats (ED50 = 1 mg/kg), an effect that can be reversed by AGN 193109, increases pinnal epidermal thickness and tail epidermal orthokeratosis percentage in mice from 0.6-2.6 mg/kg. Formulation: A solid. InChI: InChI=1S/C21H23N5S/c1-3-15(4-2)20(26-14-22-13-23-26)16-9-11-17(12-10-16)24-21-25-18-7-5-6-8-19(18)27-21/h5-15,20H,3-4H2,1-2H3,(H,24,25). InChIKey: SNFYYXUGUBUECJ-UHFFFAOYSA-N. SMILES: CCC(CC)C(C1=CC=C(NC2=NC3=CC=CC=C3S2)C=C1)N4N=CN=C4

Schlagworte:	R115866, Rambazole, N-[4-[2-ethyl-1-(1H-1,2,4-triazol-1-yl)butyl]phenyl]-2-benzothiazolamine
Hersteller:	Cayman Chemical
Hersteller-Nr:	42372

Eigenschaften

Anwendung:	CYP26 inhibitor
Immunogen:	377.51
MW:	377.51 D
Formel:	C21H23N5S
Reinheit:	>95%
Format:	Solid

Datenbank Information

CAS :	201410-53-9\| Passende Produkte
KEGG ID :	K07437 \| Passende Produkte

Handhabung & Sicherheit

Lagerung:	-20°C
Versand:	+20°C (International: -20°C)
Signalwort:	Warning
GHS-Piktogramme:
H-Sätze:	H302, H315, H319, H335
P-Sätze:	P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P362+364, P403+233, P405, P501