SR 11302

SR 11302 is a synthetic retinoid that inhibits AP-1 activity without activating transcription through RARE. It significantly suppresses both AP-1 activation and phorbol ester-induced papilloma formation in mice when applied topically (0.1 µM). SR 11302 is used to elucidate the role of AP-1 in various signaling pathways.Formal Name: (2E,4E,6Z,8E)-3-methyl-7-(4-methylphenyl)-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid. CAS Number: 160162-42-5. Molecular Formula: C26H32O2. Formula Weight: 376.5. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMF:PBS(pH7.2) (1:2): 0.33 mg/ml, DMSO: 10 mg/ml, Ethanol: 0.5 mg/ml. lambdamax: 232, 360 nm. SMILES: CC1=C(/C=C/C(C2=CC=C(C)C=C2)=C/C=C/C(C)=C/C(O)=O)C(C)(C)CCC1. InChi Code: InChI=1S/C26H32O2/c1-19-11-13-23(14-12-19)22(10-6-8-20(2)18-25(27)28)15-16-24-21(3)9-7-17-26(24,4)5/h6,8,10-16,18H,7,9,17H2,1-5H3,(H,27,28)/b8-6+,16-15+,20-18+,22-10-. InChi Key: RQANARBNMTXCDM-DKOHIBGUSA-N.