Sonepiprazole

Description: Sonepiprazole (PNU-101387G) is a chemical compound known for its selective antagonistic properties toward D4 dopamine receptors, exhibiting dissociation constants (Kis) of 3.6 nM and 10.1 nM for rat D4 (rD4) and human D4.2 (hD4.2) dopamine receptors, respectively, it shows significantly less affinity for rat D2 (rD2) dopamine and Histamine-H1 receptors, with Kis of 5147 nM and 7430 nM, respectively. Target: Dopamine Receptor. Smiles: C(CN1CCN(CC1)C2=CC=C(S(N)(=O)=O)C=C2)[C@H]3C=4C(CCO3)=CC=CC4