SLU-PP-332

Description: SLU-PP-332 is a pan-estrogen receptor-related receptor (ERR) agonist with high affinity for ERRalpha, ERRbeta, and ERRgamma, exhibiting EC50 values of 98, 230, and 430 nM, respectively. SLU-PP-332 enhances mitochondrial function and cellular respiration, increases type IIa oxidized skeletal muscle fibers, and enhances exercise tolerance in skeletal muscle cell lines. It has potential applications in the study of metabolic diseases, improvement of muscle function, and amelioration of metabolic disorders and aging. Target: Estrogen/progestogen Receptor. Smiles: C(=NNC(=O)C1=CC=C(O)C=C1)C2=CC3=C(C=C2)C=CC=C3