SH-42

Description: SH-42 is a human Delta24-dehydrocholesterol reductase (DHCR24) inhibitor (IC50: 42 nM) that is selective and highly potent in inducing an increase in plasma desmethylferricinol levels. Target: Others. Smiles: C[C@@]12[C@@]3(C([C@]4([C@](C)(CC3)[C@@]([C@@H](COC=O)C)(CC4)[H])[H])=CC[C@]1(C[C@@H](OC(C)=O)CC2)[H])[H]. References: Müller C, et al. New chemotype of selective and potent inhibitors of human delta 24-dehydrocholesterol reductase. Eur J Med Chem. 2017 Nov 10,140:305-320.