SDZ 220-040

SDZ 220-040 is an NMDA receptor antagonist (apparent pA2 = 8.75). It reduces the number of convulsions induced by maximal electroshock (MES) in mice (ED50 = 3.2-10 mg/kg). SMILES ClC1=C(C=CC(Cl)=C1)C2=CC(C[C@H](N)C(O)=O)=C(C(CP(O)(O)=O)=C2)O InChi Code InChI=1S/C16H16Cl2NO6P/c17-11-1-2-12(13(18)6-11)8-3-9(5-14(19)16(21)22)15(20)10(4-8)7-26(23,24)25/h1-4,6,14,20H,5,7,19H2,(H,21,22)(H2,23,24,25)/t14-/m0/s1 InChi Key NYZFUZCCDOSQBG-AWEZNQCLSA-N