Scoulerine

Description: Scoulerine is an inhibitor of ß-site amyloid precursor protein cleaving enzyme 1(BACE1). Scoulerine a potent antimitotic compound that inhibits proliferation, arrests cell cycle, and induces apoptosis in cancer cells. Target: Parasite, Apoptosis, Beta-Secretase, BACE. Smiles: [H][C@@]12Cc3ccc(OC)c(O)c3CN1CCc1cc(OC)c(O)cc21. References: Chlebek J, et al. Cytotoxicity of Naturally Occurring Isoquinoline Alkaloids of Different Structural Types. Nat Prod Commun. 2016 Jun,11(6):753-6.