SB-268262

A nonpeptide CGRP receptor antagonist (IC50 = 0.24 µM in a radioligand binding assay), inhibits CGRP-induced cAMP accumulation in SK-N-MC membrane preparations (IC50 = 0.83 µM). Formulation: A solid. InChI: InChI=1S/C18H15N3O4S2/c1-12-5-3-4-6-14(12)20(2)17(22)13-7-8-16(15(11-13)21(23)24)27(25)18-19-9-10-26-18/h3-11H,1-2H3. InChIKey: YXHLPJQQPOMPGE-UHFFFAOYSA-N. SMILES: O=C(N(C)C1=C(C=CC=C1)C)C2=CC=C(S(C3=NC=CS3)=O)C([N+]([O-])=O)=C2