Salinamide A

Description: Salinamide A is an effective anti-inflammatory bicyclic depsipeptide. Target: Others. Smiles: [H][C@]12COC(=O)CNC(=O)\C=C/[C@]3(CO3)[C@@H](C)Oc3ccc(cc3)[C@]([H])(NC(=O)[C@]([H])(NC(=O)[C@@H](NC(=O)[C@H](C)[C@H](O)C(C)C)[C@@H](C)OC1=O)[C@@H](C)CC)C(=O)N(C)[C@@H](Cc1ccccc1)C(=O)N[C@]([H])([C@@H](C)O)C(=O)N2 , c:10, . References: Degen D, Feng Y, Zhang Y, Ebright KY, Ebright YW, Gigliotti M, Vahedian-Movahed H, Mandal S, Talaue M, Connell N, Arnold E, Fenical W, Ebright RH. Transcription inhibition by the depsipeptide antibiotic salinamide A. Elife. 2014 Apr 30,3:e02451. doi: 10.7554/eLife.02451. PubMed PMID: 24843001, PubMed Central PMCID: PMC4029172.